What tests should I take with anemia?
In iron deficiency anemia, the values of transferrin and ferritin are of particular importance. These values can be determined if a biochemical blood test is performed.
Ferritin and anemia
Ferritin is responsible for storing and synthesizing iron for cells. If you count the amount of this substance in the blood, you can clarify the level of iron in the body as a whole.
In healthy men this value remains at the level of 20-250 μg / l, and in women at the level of 10-120 μg / l. If the values of ferritin are below these limits, then this is a sign of iron deficiency anemia.
Transferritin and anemia
Transferritin is necessary for the body to transport iron to its destination. If the amount of this protein component of blood drops, then the level of iron decreases. At the same time, it can enter the body in sufficient quantities, but it will not bind in the blood.
Normally, the level of transferritin remains at the level of 2.0-4.0 g / l. If these values are exceeded, then it is possible to suspect iron deficiency anemia. With aplastic and hypoplastic anemia, the ferritin level decreases.
It is the level of transferrin that gives the doctor a maximum of information about how iron metabolism actually takes place in the body and whether there are any violations in this process. To conduct research, the laboratory must have special equipment, which is not always available. Therefore, sometimes doctors resort to the study of the iron-binding capacity of blood. Normally, this indicator should be in the range of 20-63 μmol / l.
Auxiliary Diagnostic Studies
To clarify the diagnosis, the doctor can refer the patient to the delivery of additional tests, among which:
Determination of markers of inflammation. This study is indicated if there is a rheumatic or autoimmune disease.
Calculation of the number of folilitas and vitamin B12.
Compulsory complex diagnostics of the body should be performed to prescribe adequate treatment. The point is that iron preparations should not be used for all kinds of anemia. So first you need to establish its variety.
Studies that can be assigned:
Microscopic examination of the blood smear.
Ultrasound examination of internal organs.
Puncture of the bone marrow.
Carrying out the FGD of the stomach and intestines.
Urine collection for analysis.
The conducted researches will allow to establish, what exactly has provoked the development of anemia. If there is a suspicion of folic deficiency anemia, this vitamin is counted in erythrocytes. If necessary, the diagnosis is refined with a bone marrow puncture.
If there is a suspicion of developing B12-deficient anemia, then determine the level of this vitamin in the blood. If it is not possible to perform the research, an aspiration biopsy is performed.
On hemolytic anemia, you will need to pass urine, which determines the level of bilirubin. Also, its values in the blood serum are clarified, Kumbas is being tested.
Analyzes and studies that are required to be performed if there is a suspicion of hemolytic anemia: the determination of bilirubin in the blood and urine, ultrasound of the liver and spleen.
If the doctor assumes that the anemia is triggered by an inflammatory reaction, then in addition to standard studies, he will assign the patient to donate blood to ferritin and determine the level of C-reactive protein. This will reveal a latent inflammatory reaction.
. Without laboratory diagnostics it is impossible to detect anemia and clarify its nature. Only qualitative and high-grade inspection will allow to appoint to the patient adequate and effective treatment.