Symptoms of toxocariasis in adults and treatment

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Diagnosis of toxocarosis

It is extremely difficult to suspect the presence of toxocar in the body for these symptoms. Larvae can not be found in feces, since they do not parasitize the human colon. It is not possible to isolate them from the tissues in vivo, since such a procedure is extremely painful and traumatic. The most accurate method of diagnosing toxocarias is testing the patient’s blood for specific antibodies. If the titer of antibodies to toxocarosis is equal to 1: 800 and higher, this indicates a high probability of the disease. Additionally, the level of eosinophils in the blood is examined.

The infectious physician analyzes the results of laboratory studies and clinical manifestations and conducts differential diagnostics with the following pathologies:

  • Human helminthoses at an early stage (ascaridosis, opisthorchiasis, schistosomiasis).

  • Nonspecific polyarthritis

  • Cancer

  • Fibroplastic myocarditis

  • Lymphogranulomatosis

  • Sensitization by medicines

The decisive argument for collecting an anamnesis may be the dog in the patient’s home, his frequent contact with the ground, work on the household plot.

Additional methods of diagnosing toxocariasis:

  • Analysis on blood biochemistry total protein and other blood components.

  • Sputum examination in visceral form of the disease microscopic examination fixes on Helminths in the respiratory tract.

  • US of the abdominal cavity – fixes enlargement of the size of the spleen and liver, inflammatory process in the pancreas.

  • X-ray examination of the chest – the appearance of dense tissue sites that migrate over time is traced in the image.

  • CT, MRT – fix specifically modified tissues with inflammation sites containing larvae. / p

  • Ophthalmoscopy – detection of foreign inclusions in the eye examination.

h2 Treatment ksokaroza

Currently, there is no specific therapy for this helminthiosis. Infectious people use the following modern drugs for the treatment of toxocarosis:

Vermox (Metobendazole)

Assign 100 mg 2 r./day, apply for 2-4 weeks, side effects in the form of nausea and headache are extremely rare.

Mintezol (Tiabendazole)

Apply for 5-10 days at 50 mg / kg / day, the drug has short-term side effects, does not adversely affect the respiratory and cardiovascular system.

Ditrazine (diethylcarbamazine)

Apply for 2-4 weeks at 4-6 mg / kg / day, are shown such side effects as fever, nausea, headache and dizziness.

Nemozol (albendazole)

It is used for 10-20 days at 10 mg / kg / day, occasionally there are such side effects such as diarrhea, nausea, abdominal pain, has a teratogenic effect, is not prescribed to pregnant women.

Treatment of toxicosis in adults in an inpatient setting is performed if they are diagnosed with severe complications. With latent (latent) or erased current therapy, toxocarias are performed on an outpatient basis. The mass death of larvae leads to a violent reaction of immunity in the form of an allergic reaction. Therefore, regardless of the severity of the lesion, the patient is prescribed antihistamines. At the same time, a diet that excludes brightly colored vegetables, citrus fruits, wine, cheese, spices is prescribed.

Treatment of toxocarosis involves the use of other drugs aimed both at the cause of the disease, and on restoring the body, to relieve the human condition.

Groups of drugs for drug treatment of toxocarosis:

Etiotropic – directly affects the cause of the disease – toxocara larvae, causing her death

  • Mebendazole – is used in children over 2 years of age and in adults (see the review of tablets from worms)

  • Albendazole is approved for use in patients after the first year of life.

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Pathogenetic – restores diseased processes in the body or stops their further development

  • Glucocorticoids (prednisolone, dexamethasone) – have a powerful anti-inflammatory and anti-allergic actions.

  • Solutions of electrolytes (saline, potassium chloride, sodium acetate) – are administered intravenously in severe forms toxocarosis for the elimination of symptoms of intoxication

  • Lacto- and bifidobacteria preparations – restore the intestinal microflora for stool normalization in the visceral form of toxocarosis.

  • Adsorbents (smecta, enterol) – they are taken inside to remove toxins from the intestine.

Symptomatic – facilitates the patient’s condition, but does not affect the cause of the disease or its course

  • Antipyretic drugs (ibuprofen, paracetamol) normalize body temperature, eliminate muscle aches and joints.

  • Spazmo lytics (drotaverine, papaverine). stop pain in the abdomen with spastic reduction of bile ducts. Anti-emetic (metoclopramide, domperidone) normalize the motility of the gastrointestinal tract, stop vomiting.

  • Antiallergic (cetirizine, ketotifen ). Eliminate skin itch and rash.

Criteria for the effectiveness of anthelminthic therapy:

  • Clinical manifestations of toxocariasis (body temperature, intoxication and allergic reaction, respiratory failure) regress.

  • The level of eosinophils in the blood decreases.

  • Serum antigen levels to toxocarosis after 3-4 month after the start of treatment is 1: 8000 and below .. If the laboratory and clinical indicators improve slowly, then after 3-4 months the treatment course is repeated. In severe cases, up to 5 courses of anthelmintic therapy are required. This disease has a favorable development, ending with the recovery of the infected person. In rare cases, with severe damage to vital organs, a lethal outcome is possible.

    Toxocarosis prophylaxis

    Toxocarosis is under special control in Gossanepidnadzor. Each case of this type of helminthiasis is recorded in the reporting system. To solve the medical-veterinary problem, special preventive measures are applied:

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