What are Scleroderma
h Scleroderma causes and symptoms
Scleroderma is a disease in which the connective tissue is afflicted. The disease manifests itself in the form of seals. The causes of scleroderma, unfortunately, have not been fully understood yet.
The causes of scleroderma
p The causes that contribute to the development of scleroderma include stress situations, hypothermia, severe and chronic infectious diseases , irradiation, chemical preparations.
An important role in the development of the disease is played by dysfunction of fibroblasts and other cells that secrete collagen. The main importance is the reaction of the autoimmune system to collagen. Presumably, various disorders of the endocrine system, metabolism and others, together with the negative impact of external factors, create favorable conditions for the development of pathologies in the connective tissue system, both the skin and vessels, and the digestive organs, liver, lungs, etc.
Symptoms of scleroderma
The focal form is manifested in the form of a small number of rounded lesions. In the course of development of scleroderma they go through three stages: first appear spots, then they turn into plaques, and atrophies occur. At the beginning of scleroderma is weak: there is one or several spots of lilac-pink color, round or oval. Further in the center of the stain a compaction is formed, which with the course of the disease turns into a dense plaque with a smooth shiny surface of white or yellowish color.
Systemic and limited scleroderma are considered the most common and more recognized species.
Systemic scleroderma affects many human organs and tissues.
There is a kind of systemic scleroderma, called diffuse. This rare form is found in only five percent of patients. This form is dangerous because negative changes occur in the internal organs, so the outcome is sad.
Limited scleroderma is usually reflected on the skin and adjacent layers, although other parts of the body do not suffer.
Plaque scleroderma is one of the types of localized scleroderma. Some spots are formed. Very often the spots appear exactly where the skin was damaged. Very rarely, however, it happens that this scleroderma passes by itself.
Linear scleroderma usually affects babies. The site of the localization of the disease is the forehead, with the course of the disease it moves towards the hair. In the case of manifestation of scleroderma on the legs, trophic ulcers may occur. It happens that several people suffer from this disease in the family. Rarely does the ring-shaped form of the disease occur.
The generalized form of scleroderma affects large areas of the body. It is very common in children, although adults are also immune from this disease.
The disease of white spots usually occurs in women. Children suffer quite infrequently.
With subcutaneous morphae, the skin becomes thick and rough. With the delivery of blood for analysis, the picture changes. Complications of scleroderma
Scleroderma affects almost all organs and systems of a person. Therefore, this disease is considered difficult to cure.
Initially, of scleroderma, of course, skin suffers. On this basis, this disease is diagnosed. The standard picture is swollen and reddened areas of skin on the head and hands. In addition, often in these areas, blood circulation is disrupted, abscesses appear, the shape of the nail changes, hair falls out. Changing facial features, wrinkles appear. The skin loses its qualities. It happens that the disease captures not only the head and hands, but also other parts of the body. In this case, the disease is called diffuse scleroderma, if only certain parts of the body are affected, then this is limited scleroderma.
It happens that the disease affects the muscular system. From this, the muscle fibers are deformed, some fragments die, the volume of muscle tissue becomes smaller, and the ligaments, on the contrary, become larger.
If the disease gives a complication to the human skeleton, the fingers on all the extremities are deformed. This is also one of the signs of scleroderma.
Approximately 50% of patients with scleroderma suffer from the digestive tract. If you perform ultrasound of these organs and their changes are detected, this will also be a sign of scleroderma.
In addition, almost two-thirds of patients have heart and lung problems.